New Research Group
Johannes Stigler, a fellow of the DFG Emmy Noether Program, has just arrived at the Gene Center. His lab will use single molecule techniques to study the folding of chromosomes. Johannes has also won an ERC starting grant to support his research.
Stigler lab - Biophysics of Chromosome Folding
Chromosomes provide the fundamental scaffold for the maintenance, regulation and propagation of genetic information. Recent experimental findings have shown that eukaryotic chromosomes are folded in three-dimensional space and that the three-dimensional folding of chromosomes is directly linked to gene regulation. Our lab uses biophysical single molecule techniques, such as optical tweezers and fluorescence microscopy by DNA curtains to determine the processes that lead to the three-dimensional folding of chromosomes.
For more Information please visit the Stigler lab website