Stefan Oehlers - Institute for Infectious Diseases, Sydney
Insights into mycobacterial pathogenesis from zebrafish infection models
12.09.2022 at 13:00
Gene Center Seminar Series
Host:
Joseph Bartho
Location:
Gene Center Munich
Ludwig-Maximilians-Universität München
Lynen Lecture Hall (A 0.75)
Feodor-Lynen-Straße 25
81377 Munich
Germany
Abstract:
The zebrafish model system is an important platform for studying both early events in mycobacterial infection due to the visual accessibility of embryo hosts and the complex multicellular events that drive granuloma formation due to their coevolution with natural mycobacterial pathogens. I will talk about insights into macrophage control of mycobacterial infection provided by our use of the established zebrafish-M. marinum infection model and the immunopathogenesis of Mycobacterium abscessus infection using our newly described adult zebrafish model of persistent infection.