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Perocchi Lab - Publications

2018   |   2017   |   2016   |   2015   |   2014   |   2013   |   2011   |   2010   |   2009   |   2008   |   2007   |   2006   |


2018





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2017

SK2 channels regulate mitochondrial respiration and mitochondrial Ca(2+) uptake.
Honrath B, Matschke L, Meyer T, Magerhans L, Perocchi F, Ganjam GK, Zischka H, Krasel C, Gerding A, Bakker BM, Bünemann M, Strack S, Decher N, Culmsee C, Dolga AM.
Cell Death Differ. 2017 May;24(5):761-773. doi: 10.1038/cdd.2017.2. Epub 2017 Mar 10. PubMed

Isolation of Functional Mitochondria from Cultured Cells and Mouse Tissues.
Wettmarshausen J, Perocchi F.
Methods Mol Biol. 2017;1567:15-32. doi: 10.1007/978-1-4939-6824-4_2. PubMed

Synthetic Methods for the Preparation of a Functional Analogue of Ru360, a Potent Inhibitor of Mitochondrial Calcium Uptake.
Nathan SR, Pino NW, Arduino DM, Perocchi F, MacMillan SN, Wilson JJ.
Inorg Chem. 2017 Mar 20;56(6):3123-3126. doi: 10.1021/acs.inorgchem.6b03108. Epub 2017 Feb 28. PubMed

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2016

K(+) Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria.
Groß CJ, Mishra R, Schneider KS, Médard G, Wettmarshausen J, Dittlein DC, Shi H, Gorka O, Koenig PA, Fromm S, Magnani G, Cikovic T, Hartjes L, Smollich J, Robertson AA, Cooper MA, Perocchi F, Schmidt-Supprian M, Schuster M, Schroder K, Broz P, Traidl-Hoffmann C, Beutler B, et al.
Immunity. 2016 Oct 18;45(4):761-773. doi: 10.1016/j.immuni.2016.08.010. Epub 2016 Sep 27. PubMed

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2015

Meclizine Preconditioning Protects the Kidney Against Ischemia-Reperfusion Injury.
Kishi S, Campanholle G, Gohil VM, Perocchi F, Brooks CR, Morizane R, Sabbisetti V, Ichimura T, Mootha VK, Bonventre JV.
EBioMedicine. 2015 Jul 29;2(9):1090-101. doi: 10.1016/j.ebiom.2015.07.035. eCollection 2015 Sep. PubMed

ProtPhylo: identification of protein-phenotype and protein-protein functional associations via phylogenetic profiling.
Cheng Y, Perocchi F.
Nucleic Acids Res. 2015 Jul 1;43(W1):W160-8. doi: 10.1093/nar/gkv455. Epub 2015 May 8. PubMed

Prediction of mitochondrial protein function by comparative physiology and phylogenetic profiling.
Cheng Y, Perocchi F.
Methods Mol Biol. 2015;1264:321-9. doi: 10.1007/978-1-4939-2257-4_28. PubMed

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2014

MRM2 and MRM3 are involved in biogenesis of the large subunit of the mitochondrial ribosome.
Rorbach J, Boesch P, Gammage PA, Nicholls TJ, Pearce SF, Patel D, Hauser A, Perocchi F, Minczuk M.
Mol Biol Cell. 2014 Sep 1;25(17):2542-55. doi: 10.1091/mbc.E14-01-0014. Epub 2014 Jul 9. PubMed

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2013

MICU1 controls both the threshold and cooperative activation of the mitochondrial Ca²⁺ uniporter.
Csordás G, Golenár T, Seifert EL, Kamer KJ, Sancak Y, Perocchi F, Moffat C, Weaver D, de la Fuente Perez S, Bogorad R, Koteliansky V, Adijanto J, Mootha VK, Hajnóczky G.
Cell Metab. 2013 Jun 4;17(6):976-87. doi: 10.1016/j.cmet.2013.04.020. PubMed

Mitochondrial small conductance SK2 channels prevent glutamate-induced oxytosis and mitochondrial dysfunction.
Dolga AM, Netter MF, Perocchi F, Doti N, Meissner L, Tobaben S, Grohm J, Zischka H, Plesnila N, Decher N, Culmsee C.
J Biol Chem. 2013 Apr 12;288(15):10792-804. doi: 10.1074/jbc.M113.453522. Epub 2013 Feb 19. PubMed

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2011

Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter.
Baughman JM, Perocchi F, Girgis HS, Plovanich M, Belcher-Timme CA, Sancak Y, Bao XR, Strittmatter L, Goldberger O, Bogorad RL, Koteliansky V, Mootha VK.
Nature. 2011 Jun 19;476(7360):341-5. doi: 10.1038/nature10234. PubMed

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2010

MICU1 encodes a mitochondrial EF hand protein required for Ca(2+) uptake.
Perocchi F, Gohil VM, Girgis HS, Bao XR, McCombs JE, Palmer AE, Mootha VK.
Nature. 2010 Sep 16;467(7313):291-6. doi: 10.1038/nature09358. Epub 2010 Aug 8. PubMed

Nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis.
Gohil VM, Sheth SA, Nilsson R, Wojtovich AP, Lee JH, Perocchi F, Chen W, Clish CB, Ayata C, Brookes PS, Mootha VK.
Nat Biotechnol. 2010 Mar;28(3):249-55. doi: 10.1038/nbt.1606. Epub 2010 Feb 14. PubMed

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2009

Genome-wide allele- and strand-specific expression profiling.
Gagneur J, Sinha H, Perocchi F, Bourgon R, Huber W, Steinmetz LM.
Mol Syst Biol. 2009;5:274. doi: 10.1038/msb.2009.31. Epub 2009 Jun 16. PubMed

Bidirectional promoters generate pervasive transcription in yeast.
Xu Z, Wei W, Gagneur J, Perocchi F, Clauder-Münster S, Camblong J, Guffanti E, Stutz F, Huber W, Steinmetz LM.
Nature. 2009 Feb 19;457(7232):1033-7. doi: 10.1038/nature07728. Epub 2009 Jan 25. PubMed

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2008

Systematic screens for human disease genes, from yeast to human and back.
Perocchi F, Mancera E, Steinmetz LM.
Mol Biosyst. 2008 Jan;4(1):18-29. Epub 2007 Sep 25. Review. PubMed

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2007

Antisense artifacts in transcriptome microarray experiments are resolved by actinomycin D.
Perocchi F, Xu Z, Clauder-Münster S, Steinmetz LM.
Nucleic Acids Res. 2007;35(19):e128. Epub 2007 Sep 26. PubMed

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2006

Assessing systems properties of yeast mitochondria through an interaction map of the organelle.
Perocchi F, Jensen LJ, Gagneur J, Ahting U, von Mering C, Bork P, Prokisch H, Steinmetz LM.
PLoS Genet. 2006 Oct 20;2(10):e170. PubMed