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Ferraz Lab - Biology of Reproduction

ferraz_mainResearch Topics

  • 3D models of Reproductive tissues
  • Extracellular vesicles in reproduction
  • Bio-printing and microfluidics
  • Microplastics and fertility

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Declining fertility in humans together with unknown causes of reproductive disease, effects of environmental stressors, and threats to survival of endangered species, all call for advancements in reproduction research. Our lab uses new technologies, such as bio-printing and organs-on-a-chip, to create dynamic reproductive models with both basic and translatable outcomes that span biomedical, agricultural and wildlife sciences. Read more...

Selected Publications

Understanding and Assisting Reproduction in Wildlife Species Using Microfluidics.
Le Gac S, Ferraz MAMM, Venzac B, Comizzoli P.
Trends Biotechnol. 2020 Oct 7:S0167-7799(20)30234-1. doi: 10.1016/j.tibtech.2020.08.012. PubMed

A dog oviduct-on-a-chip model of serous tubal intraepithelial carcinoma.
Ferraz MAMM, Nagashima JB, Venzac B, Le Gac S, Songsasen N.
Sci Rep. 2020 Jan 31;10(1):1575. doi: 10.1038/s41598-020-58507-4. PubMed

An oviduct-on-a-chip provides an enhanced in vitro environment for zygote genome reprogramming.
Ferraz MAMM, Rho HS, Hemerich D, Henning HHW, van Tol HTA, Hölker M, Besenfelder U, Mokry M, Vos PLAM, Stout TAE, Le Gac S, Gadella BM.
Nat Commun. 2018 Nov 22;9(1):4934. doi: 10.1038/s41467-018-07119-8. PubMed

Potential Health and Environmental Risks of Three-Dimensional Engineered Polymers.
Ferraz MAMM, Henning HHW, Ferreira da Costa P, Malda J, Le Gac S, Bray F, van Duursen MBM, Brouwers JF, van de Lest CHA, Bertijn I, Kraneburg L, Vos PLAM, Stout TAE, Gadella BM.
Environ Sci Technol Lett. 2018 Feb 13;5(2):80-85. doi: 10.1021/acs.estlett.7b00495. PubMed

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