Halic Lab - Publications
2019 | 2018 | 2017 | 2016 | 2013 | 2010 | 2009 | 2006 | 2005 | 2004
2019
Disordered region of H3K9 methyltransferase Clr4 binds the nucleosome and contributes to its activity.
Akoury E, Ma G, Demolin S, Brönner C, Zocco M, Cirilo A, Ivic N, Halic M.
Nucleic Acids Res. 2019 Jul 26;47(13):6726-6736. doi: 10.1093/nar/gkz480. PubMed
Fuzzy Interactions Form and Shape the Histone Transport Complex.
Ivic N, Potocnjak M, Solis-Mezarino V, Herzog F, Bilokapic S, Halic M.
Mol Cell. 2019 Mar 21;73(6):1191-1203.e6. doi: 10.1016/j.molcel.2019.01.032. Epub 2019 Feb 26. PubMed
Shelterin and subtelomeric DNA sequences control nucleosome maintenance and genome stability.
van Emden TS, Forn M, Forné I, Sarkadi Z, Capella M, Martín Caballero L, Fischer-Burkart S, Brönner C, Simonetta M, Toczyski D, Halic M, Imhof A, Braun S.
EMBO Rep. 2019 Jan;20(1). pii: e47181. doi: 10.15252/embr.201847181. Epub 2018 Nov 12. PubMed
2018
Fidelity in RNA-based recognition of transposable elements.
Ugolini I, Halic M.
Philos Trans R Soc Lond B Biol Sci. 2018 Nov 5;373(1762). pii: 20180168. doi: 10.1098/rstb.2018.0168. Review. PubMed
Cryo-EM of nucleosome core particle interactions in trans.
Bilokapic S, Strauss M, Halic M.
Sci Rep. 2018 May 4;8(1):7046. doi: 10.1038/s41598-018-25429-1. PubMed
Structural rearrangements of the histone octamer translocate DNA.
Bilokapic S, Strauss M, Halic M.
Nat Commun. 2018 Apr 6;9(1):1330. doi: 10.1038/s41467-018-03677-z. PubMed
Histone octamer rearranges to adapt to DNA unwrapping.
Bilokapic S, Strauss M, Halic M.
Nat Struct Mol Biol. 2018 Jan;25(1):101-108. doi: 10.1038/s41594-017-0005-5. Epub 2017 Dec 11. PubMed
2017
Preparative two-step purification of recombinant H1.0 linker histone and its domains.
Ivic N, Bilokapic S, Halic M.
PLoS One. 2017 Dec 5;12(12):e0189040. doi: 10.1371/journal.pone.0189040. eCollection 2017. PubMed
Tailing and degradation of Argonaute-bound small RNAs protect the genome from uncontrolled RNAi.
Pisacane P, Halic M.
Nat Commun. 2017 May 25;8:15332. doi: 10.1038/ncomms15332. PubMed
Accumulation of RNA on chromatin disrupts heterochromatic silencing.
Brönner C, Salvi L, Zocco M, Ugolini I, Halic M.
Genome Res. 2017 Apr 12. doi: 10.1101/gr.216986.116. [Epub ahead of print] PubMed
2016
The Chp1 chromodomain binds the H3K9me tail and the nucleosome core to assemble heterochromatin.
Zocco M, Marasovic M, Pisacane P, Bilokapic S, Halic M.
Cell Discov. 2016 Apr 19;2:16004. doi: 10.1038/celldisc.2016.4. eCollection 2016. PubMed
2013
Argonaute and Triman generate dicer-independent priRNAs and mature siRNAs to initiate heterochromatin formation.
Marasovic M, Zocco M, Halic M.
Mol Cell. 2013 Oct 24;52(2):173-83. doi: 10.1016/j.molcel.2013.08.046. Epub 2013 Oct 3. PubMed
2010
The methyltransferase activity of Clr4Suv39h triggers RNAi independently of histone H3K9 methylation.
Gerace EL, Halic M, Moazed D.
Mol Cell. 2010 Aug 13;39(3):360-72. doi: 10.1016/j.molcel.2010.07.017. PubMed
Dicer-independent primal RNAs trigger RNAi and heterochromatin formation.
Halic M, Moazed D.
Cell. 2010 Feb 19;140(4):504-16. doi: 10.1016/j.cell.2010.01.019. PubMed
alpha-Helical nascent polypeptide chains visualized within distinct regions of the ribosomal exit tunnel.
Bhushan S, Gartmann M, Halic M, Armache JP, Jarasch A, Mielke T, Berninghausen O, Wilson DN, Beckmann R.
Nat Struct Mol Biol. 2010 Mar;17(3):313-7. doi: 10.1038/nsmb.1756. Epub 2010 Feb 7. PubMed
2009
22G-RNAs in transposon silencing and centromere function.
Halic M, Moazed D.
Mol Cell. 2009 Oct 23;36(2):170-1. doi: 10.1016/j.molcel.2009.10.010. PubMed
Transposon silencing by piRNAs.
Halic M, Moazed D.
Cell. 2009 Sep 18;138(6):1058-60. doi: 10.1016/j.cell.2009.08.030. PubMed
2006
Following the signal sequence from ribosomal tunnel exit to signal recognition particle.
Halic M, Blau M, Becker T, Mielke T, Pool MR, Wild K, Sinning I, Beckmann R.
Nature. 2006 Nov 23;444(7118):507-11. Epub 2006 Oct 29. PubMed
Structure of eEF3 and the mechanism of transfer RNA release from the E-site.
Andersen CB, Becker T, Blau M, Anand M, Halic M, Balar B, Mielke T, Boesen T, Pedersen JS, Spahn CM, Kinzy TG, Andersen GR, Beckmann R.
Nature. 2006 Oct 12;443(7112):663-8. Epub 2006 Aug 23. PubMed
Signal recognition particle receptor exposes the ribosomal translocon binding site.
Halic M, Gartmann M, Schlenker O, Mielke T, Pool MR, Sinning I, Beckmann R.
Science. 2006 May 5;312(5774):745-7. PubMed
2005
Localization and dynamic behavior of ribosomal protein L30e.
Halic M, Becker T, Frank J, Spahn CM, Beckmann R.
Nat Struct Mol Biol. 2005 May;12(5):467-8. Epub 2005 May 1. PubMed
The signal recognition particle and its interactions during protein targeting.
Halic M, Beckmann R.
Curr Opin Struct Biol. 2005 Feb;15(1):116-25. Review. PubMed
2004
SRP meets the ribosome.
Wild K, Halic M, Sinning I, Beckmann R.
Nat Struct Mol Biol. 2004 Nov;11(11):1049-53. Review. PubMed
Structure of the signal recognition particle interacting with the elongation-arrested ribosome.
Halic M, Becker T, Pool MR, Spahn CM, Grassucci RA, Frank J, Beckmann R.
Nature. 2004 Feb 26;427(6977):808-14. PubMed