Krebs Lab - Genomics
Research Topics
- Transcriptomics of early embryonic development
- Epidemiology of Mycobacterium caprae
- Whole animal transcriptomics of disease models
High-throughput sequencing (NGS) has become an indispensable tool for biomedical research by allowing detailed analyses of transcriptomes and genomes and providing readouts for molecular, cellular, and organismal biological processes. In addition to the Illumina technology, LAFUGA-Genomics also performs long-read sequencing with nanopores and offers the innovative AVITI technology for the most cost-efficient short-read production and direct in-situ single cell mRNA sequencing and multiome imaging. With this range of techniques, we support research projects across various fields, including translational biomedical research, biochemistry, immunology, virology, and archaeology. Read more...
Selected Publications
Ancient genomics and the origin, dispersal, and development of domestic sheep.
Daly KG, Mullin VE, Hare AJ, Halpin Á, Mattiangeli V, Teasdale MD, Rossi C, Geiger S, Krebs S, Medugorac I, Sandoval-Castellanos E, Özbaşaran M, Duru G, Gülcür S, Pöllath N, Collins M, Frantz L, Vila E, Zidarov P, Stoddart S, Boldgiv B, Orlando L, Pearson MP, Mullville J, Askeyev IV, Askeyev AO, Askeyev OV, Shaymuratova DN, Van den Hurk Y, Zeeb-Lanz A, Arbogast RM, Hemmer H, Davoudi H, Amiri S, Doost SB, Decruyenaere D, Fathi H, Khazaeli R, Hassanzadeh Y, Sardari A, Lhuillier J, Abdolahi M, Summers GD, Marro C, Bahshaliyev V, Berthon R, Çakirlar C, Benecke N, Scheu A, Burger J, Sauer E, Horwitz LK, Arbuckle B, Buitenhuis H, Gourichon L, Bulatović J, O'Connor T, Orton D, Jalabadze M, Rhodes S, Chazan M, Özkaya V, Zeder M, Atıcı L, Mashkour M, Peters J, Bradley DG.
Science. 2025 Jan 31;387(6733):492-497. doi: 10.1126/science.adn2094. Epub 2025 Jan 30. Link
Three exposures to the spike protein of SARS-CoV-2 by either infection or vaccination elicit superior neutralizing immunity to all variants of concern.
Wratil PR, Stern M, Priller A, Willmann A, Almanzar G, Vogel E, Feuerherd M, Cheng CC, Yazici S, Christa C, Jeske S, Lupoli G, Vogt T, Albanese M, Mejías-Pérez E, Bauernfried S, Graf N, Mijocevic H, Vu M, Tinnefeld K, Wettengel J, Hoffmann D, Muenchhoff M, Daechert C, Mairhofer H, Krebs S, Fingerle V, Graf A, Steininger P, Blum H, Hornung V, Liebl B, Überla K, Prelog M, Knolle P, Keppler OT, Protzer U.
Nat Med. 2022 Mar;28(3):496-503. doi: 10.1038/s41591-022-01715-4. Epub 2022 Jan 28. Link