Contact
Gene Center
Laboratory for Translational Cancer Immunology
Ludwig-Maximilians-Universität München
Feodor-Lynen-Straße 25
81377 Munich
Germany
Laboratory for Translational Cancer Immunology
Ludwig-Maximilians-Universität München
Feodor-Lynen-Straße 25
81377 Munich
Germany
Room:
A 2.04
Phone:
+49 (0)89 - 4400 73133
Email:
marion.subklewe@med.uni-muenchen.de
Professional Experience
| Year | Function | Institute |
|---|---|---|
| since 2017 | Head of the Laboratory for Translational Cancer Immunology |
Gene Center Munich |
| since 2014 | Professor for Internal Medicine, with focus on Cellular Immunotherapy |
University Hospital, LMU Munich, Department of Medicine III |
| 2012-2017 | Head of the Clinical Cooperation Group "Immunotherapy" | Helmholtz Zentrum Munich |
| since 2009 | Head of Flow Cytometry, Laboratory of Leukemia Diagnostics |
University Hospital, LMU Munich, Department of Medicine III, Prof. Dr. W. Hiddemann |
| since 2009 | Consultant for Hematology / Oncology | University Hospital, LMU Munich, Department of Medicine III, Prof. Dr. W. Hiddemann |
| 2008-2009 | Clinical Fellow Hematology / Oncology | University Hospital, LMU Munich, Department of Medicine III, Prof. Dr. W. Hiddemann |
| 2000-2007 | Clinical Fellow Hematology / Oncology | The Charité, Campus Virchow-Klinikum, Medical Department III, Berlin, Prof. Dr. B. Dörken |
| 1996-2000 | Postdoctoral Fellow, DFG-Scholarship, Cure for Lymphoma Fellow |
Rockefeller University, New York, Prof. Dr. R. M. Steinman |
| 1995-1996 | Residency Internal Medicine | University Hospital Tübingen, Medical Department II, Hematology / Oncology / Reheumatology, Prof. Dr. L. Kanz |
Education
| 2014 | W2-Professor for Internal Medicine, with focus on Cellular Immunotherapy |
University Hospital, LMU Munich |
| 2007 | „Habilitation“ in Internal Medicine | Charité, Berlin |
| 2007 | Board Certification Hematology / Oncology | |
| 2005 | Board Certification Internal Medicine | |
| 1995 | Medical Dissertation | University of Cologne, Department of Internal Medicine, Hematology / Oncology, Prof. Dr. V. Diehl |
| 1988-1993 | Study of Medicine | University of Cologne |
| 1986-1988 | Study of Medicine | RWTH Aachen |
Awards and Honors
| 2025 | HemaSphere Award 2025 – Top Cited Clinical Article |
| 2025 | EHA Educational Presentation (AML) (also 2021, 2022, 2023) |
| 2024 | Highly Cited Researcher 2024 |
| 2024 | Dr. Robert Pfleger Research Award |
| 2023 | ASH Educational (AML) |
| 2018 | ASH Abstract Achievement Award |
| 2015 | M4-Award: Startup support for the development of a novel multispecific antibody derivative |
| 2015 | ASH Abstract Achievement Award: Identifying Immune Resistance Mechanisms to CD33/CD3 BiTE Antibody Construct (AMG 330) Mediated Cytotoxicity |
| 2014 | DGHO-Poster Prize: Addition of CD200 and Omission of sIgM Improves the Scoring System for the Diagnosis of CLL |
| 2013 | Selection for the ASH Highlights: Evaluation of CD33 expression and functional analysis of the CD33/CD3 bispecific antibody AMG 330 activity in primary AML samples |
| 2012 | Therese von Bayern-Award |
| 2011 | ASH Abstract Achievement Award: A Combined Score of Minimal Residual Disease (MRD) Assessment by Flow Cytometry, Cytogenetic and Molecular Markers As Well As Age Predicts Outcome and Can Potentially Guide MRD-Based Therapy in Acute Myeloid Leukemia |
| 2011 | ASH Abstract Achievement Award: Dendritic Cells Matured with a TLR7/8 Agonist Induce T Helper 1 Cell Polarization, Activate NK Cells and Are Thus Highly Suitable for Application in Cancer Immunotherapy |
| 2011 | Best Lecturer at the faculty of Medicine at the LMU |
| 2005-2007 | Rahel-Hirsch Scholarship at the Charité („Habilitations-Scholarship“) |
| 1999-2000 | Cure for Lymphoma Foundation Fellow |
| 1996-1999 | Postdoctoral Scholarship of the Deutsche Forschungsgemeinschaft |
Additional Functions
- Spokesperson of the Else Kröner Clinician Scientist Programm Cancer Immunotherapy - LMU Munich, fostering the development of clinician scientists in oncology/immunology by a network of expert mentors, protected time for research, seminars and travel support
- Founder and spokesperson of FAME - Female Academic Medicine providing Excellence, a female Professorship network at the Medical Faculty of the LMU
- Head of the "Molecular Oncology" module in the Elite Master Program "Human Biology – Principles in Health & Disease" offered by the Faculties of Biology and Medicine at LMU
- Principal Investigator and Sponsor delegated Person of a prospective Phase I/II I-IT “Active immunotherapy of patients with AML using autologous dendritic cells transfected with RNA encoding leukemia-associated antigens”
- Principal Investigator of a Phase I Study „A Phase 1 First-in-Human Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of AMG 330 Administered as Continuous Intravenous Infusion in Subjects with Relapsed/Refractory Acute Myeloid Leukemia“
- Principle Investigator in multiple Phase I trials (CAR T, T-cell recruiting antibodies), Principle Investigator in multiple Phase II/III trials in leukemia and lymphoma (GMALL, GLSG, DSHNHL)
- Protocol committee AML Cooperative Group (AML-CG)
- Member of the Organizing Committee of the International Symposia “Acute Leukemias”, "iTOC" and "ICLE"
- Certification (2011) and Akkreditation Flow Cytometry (2012) within the Laboratory of Leukemia Diagnostics
- Collaborative Research Activities – SFB-TRR 338 "LETs Immun" - Lymphocyte Engineering, MIRACLE - European Partnership for Personalized Medicine, MetabotargetAML by EP Per Med, Bavarian Immunotherapy Network, Helmholtz Alliance for Immunotherapy, Deutsches Konsortium für Translationale Krebsforschung, Munich Immunotherapy Consortium (MITC), Elitenetzwerk Bayern International Graduate School “Immunotargeting of Cancer”, Else-Kröner Fresenius Forschungskolleg “Cancer Immunotherapy”
- Grant Reviews - Deutsche Forschungsgemeinschaft; Deutsche Krebshilfe; José-Carreras Stiftung; Wilhelm Sander Stiftung; Cancer Research UK; Leukemia and Lymphoma; OeGHO, Dutch Cancer Society, Wordwide Cancer Research
- Manuscript Reviews - Blood, Leukemia, Lancet Hematology, NEJM, PlosOne, J International Immunology, Journal of Hematology & Oncology; Haematologica; British Journal of Hematology, Journal of Immunotherapy, PlosOne, Oncoimmunology, Blood Reviews, Blood Advances
- Membership - Bund deutscher Internisten (BdI); European Association for Hematology (EHA); American Society for Hematology (ASH); Deutsche Gesellschaft für Hämatologie und Onkologie (DGHO); Society for Immunotherapy of Cancer (SITC), Cancer for Immunotherapy (CIMT)
- Member of the “Research committee (Forschungskommission)” Klinikum der Universität München, member of several Thesis Advisory Committees